Targeting the XIAP/caspase-7 complex selectively kills caspase-3–deficient malignancies
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چکیده
منابع مشابه
Selectively Kills Tumor Cells
nloaded 1 kinase activates multiple transcription factors and regulates the level of reactive oxygen species We have previously reported that ablation of TAK1 in keratinocytes causes hypersensitivity to ROSd cell apoptosis. It is known that some tumor cells produce ROS at higher levels compared with normal e used inducible epidermal-specific TAK1 knockout mice and examined whether ablation of T...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2013
ISSN: 0021-9738
DOI: 10.1172/jci67951